Selective estrogen receptor modulators as brain therapeutic agents.
نویسندگان
چکیده
Selective estrogen receptor modulators (SERMs), used for the treatment of breast cancer, osteoporosis, and menopausal symptoms, affect the nervous system. Some SERMs trigger neuroprotective mechanisms and reduce neural damage in different experimental models of neural trauma, brain inflammation, neurodegenerative diseases, cognitive impairment, and affective disorders. New SERMs with specific actions on neurons and glial cells may represent promising therapeutic tools for the brain.
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ورودعنوان ژورنال:
- Journal of molecular endocrinology
دوره 46 1 شماره
صفحات -
تاریخ انتشار 2011